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In vivo studies on uricase activity in the rat.

Authors :
Lang, F.
Greger, R.
Deetjen, P.
Source :
Pflügers Archiv: European Journal of Physiology; 1974, Vol. 351 Issue 4, p323-330, 8p
Publication Year :
1974

Abstract

It is concluded from these results that: 1. The rat kidney has no significant uricase activity. 2. Urate transport in the kidney is not influenced by this enzyme. 3. The degradation of urate to allantoin takes place at extrarenal sites, mainly in the liver. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00316768
Volume :
351
Issue :
4
Database :
Complementary Index
Journal :
Pflügers Archiv: European Journal of Physiology
Publication Type :
Academic Journal
Accession number :
73144378
Full Text :
https://doi.org/10.1007/BF00593318