A strong signature of balancing selection in the 5' cis-regulatory region of CCR5.

Authors :: Bamshad, Michael J.
Mummidi, Srinivas
Gonzalez, Enrique
Ahuja, Seema S.
Dunn, Diane M.
Watkins, W. Scott
Wooding, Stephen
Stone, Anne C.
Jorde, Lynn B.
Weiss, Robert B.
Ahuja, Sunil K.
Source :: Proceedings of the National Academy of Sciences of the United States of America; 8/6/2002, Vol. 99 Issue 16, p10539, 6p, 2 Diagrams, 2 Charts, 2 Graphs
Publication Year :: 2002
Abstract: Examines the role of balancing selection in shaping the variation patterns of CC chemokine receptor 5 (CCR5). Association of varied HIV-1 susceptibility with polymorphisms in CCR5; Genealogy of CCR5 haplotypes; Consequences of adaptive changes in older pathogens.

Language :: English
ISSN :: 00278424
Volume :: 99
Issue :: 16
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 7310617
Full Text :: https://doi.org/10.1073/pnas.162046399

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