Fibrinogen and the ultralong-range interaction of human erythrocytes.

Fibrinogen, purified by a new method, does not transmit the ultralong-range interaction of erythrocytes. It can be converted into a transmitter by the addition of a preparation of clotting factors used clinically in the treatments of hemophilia B. It is suggested that the addition of the clotting factors induces a conformational change in fibrogen, which can then polymerize. [ABSTRACT FROM AUTHOR]