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Cardiac biomarkers in neonatal hypoxic ischaemia.

Authors :
Sweetman, D
Armstrong, K
Murphy, JFA
Molloy, EJ
Source :
Acta Paediatrica; Apr2012, Vol. 101 Issue 4, p338-343, 6p
Publication Year :
2012

Abstract

Following a perinatal hypoxic-ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin-T, troponin-I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long-term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow-up studies are warranted to ensure optimal cardiac function in adulthood. Conclusion: Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic-ischaemia. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
08035253
Volume :
101
Issue :
4
Database :
Complementary Index
Journal :
Acta Paediatrica
Publication Type :
Academic Journal
Accession number :
72366165
Full Text :
https://doi.org/10.1111/j.1651-2227.2011.02539.x