FLIP switches Fas-mediated glucose signaling in human pancreatic Β cells from apoptosis to cell replication.

Authors :: Maedler, Kathrin
Fontana, Adriano
Ris, Frédéric
Sergeev, Pavel
Toso, Christian
Oberholzer, José
Lehmann, Roger
Bachmann, Felix
Tasinato, Andrea
Spinas, Giatgen A.
Halban, Philippe A.
Donath, Marc Y.
Source :: Proceedings of the National Academy of Sciences of the United States of America; 6/11/2002, Vol. 99 Issue 12, p8236, 7p, 2 Color Photographs, 7 Diagrams, 1 Chart, 9 Graphs
Publication Year :: 2002
Abstract: Examines the genetic expression of FLIP in human pancreatic β cells of nondiabetic and diabetic patients. Role of glucose in the regulation of FLIP expression; Information on Fas receptor activation by FLIP; Inhibition of the beneficial effects of FLIP overexpression.

Language :: English
ISSN :: 00278424
Volume :: 99
Issue :: 12
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 7135481
Full Text :: https://doi.org/10.1073/pnas.122686299

Full Text Access

Tools