Back to Search
Start Over
Effects of ethnicity and vitamin D supplementation on vitamin D status and changes in bone mineral content in infants.
- Source :
- BMC Pediatrics; 2012, Vol. 12 Issue 1, p1-7, 7p, 1 Chart, 2 Graphs
- Publication Year :
- 2012
-
Abstract
- Background: To evaluate the effects on serum 25(OH)D and bone mineralization of supplementation of breast-fed Hispanic and non-Hispanic Caucasian infants with vitamin D in infants in Houston, Texas. Methods: We measured cord serum 25(OH)D levels, bone mineral content (BMC), bone mineral density (BMD) and their changes over 3 months of life with 400 IU/day of vitamin D3 supplementation. Results: Cord serum 25(OH)D was significantly lower in Hispanic than non-Hispanic Caucasian infants (16.4 ± 6.5 ng/mL, n = 27, vs 22.3 ± 9.4 n = 22, p = 0.013). Among 38 infants who completed a 3 month vitamin D supplementation intervention, provision of 400 IU/day of vitamin D increased final 25(OH)D to a higher level in non-Hispanic Caucasian compared to Hispanic infants. There was no significant relationship between cord serum 25(OH)D and BMC or BMD in the first week of life (n = 49) or after 3 months of vitamin D supplementation. Conclusion: Low cord 25(OH)D levels are seen in Hispanic infants, but their functional significance is uncertain related to bone health in a southern US setting. Daily vitamin D intake of 400 IU during the first months of life appears adequate to increase serum 25(OH)D and support BMC increases despite low initial 25(OH)D levels in some infants. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14712431
- Volume :
- 12
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- BMC Pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 71340708
- Full Text :
- https://doi.org/10.1186/1471-2431-12-6