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Tumorigenic activity of cloned polyoma virus DNA in newborn rats.

Authors :
Gélinas, C.
Bouchard, L.
Bastin, M.
Source :
Experientia; Oct1981, Vol. 37 Issue 10, p1074-1075, 2p
Publication Year :
1981

Abstract

The proximal portion of the polyoma virus early region as well as the complete viral genome were cloned in pBR322. Recombinant plasmids induced tumors in newborn rats but only after linearization of the DNA by various restriction endonucleases. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00144754
Volume :
37
Issue :
10
Database :
Complementary Index
Journal :
Experientia
Publication Type :
Academic Journal
Accession number :
70747994
Full Text :
https://doi.org/10.1007/BF02085017