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The absolute configuration of SU 23397: A novel neuroleptic agent.

Authors :
Chaudhuri, N.
Ball, T.
Finch, N.
Source :
Experientia; May1977, Vol. 33 Issue 5, p575-577, 3p
Publication Year :
1977

Abstract

The absolute configuration of a novel chiral neuroleptic agent SU 23397 ( I) was determined by ORD comparison of (+)-5-methoxy dihydro coumarilic acid ( VIII), a synthetic precursor of SU 23397 ( I), with (+)-dihydro coumarilic acid, whose absolute configuration is known. This assignment was confirmed by oxidative degradation of (+)-5-methoxy dihydro coumarilic acid VIII to d-(+)-malic acid. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00144754
Volume :
33
Issue :
5
Database :
Complementary Index
Journal :
Experientia
Publication Type :
Academic Journal
Accession number :
70743836
Full Text :
https://doi.org/10.1007/BF01946504