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Pulmonary Function and Left Ventricular Mass in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study.
- Source :
- Echocardiography; Feb2012, Vol. 29 Issue 2, p131-139, 9p
- Publication Year :
- 2012
-
Abstract
- Purpose: Impaired pulmonary function has been associated with increased cardiovascular disease incidence and mortality. The objective of this study was to investigate associations between pulmonary function and left ventricular (LV) mass. Methods: Participants were African American women (n = 1,069) and men (n = 555) aged 49-73 years, from the Atherosclerosis Risk in Communities study. Mean pulmonary function values at the first (1987-1989) and second (1990-1992) examinations were used. Echocardiograms were performed at the third and early in the fourth examinations (1993-1996). Analysis of covariance and linear regression were used to assess associations. Results: Mean levels of LV mass decreased with increasing quintiles of forced expiratory volume in one second (FEV<subscript>1</subscript>) among female never smokers (P = 0.039). Forced vital capacity (FVC) showed stronger associations than FEV<subscript>1</subscript> with LV mass. Among men, LV mass was positively associated with FEV<subscript>1</subscript> among current and never smokers, and with FVC among never smokers. Additional analyses among never smokers revealed significant inverse associations between LV mass and FVC among women with waist-to-hip ratios of >0.85 and those with no history of diabetes. In contrast, significant positive associations between LV mass and FVC were seen among male never smokers with body mass index (BMI) of ≤24.9 kg/m<superscript>2</superscript>, waist-to-hip ratios of ≤0.95, no history of hypertension or diabetes, and ≤60 years old. BMI and waist-to-hip ratio significantly modified associations among men. Conclusions: Among never smokers, LV mass and pulmonary function were inversely associated among women and positively associated among men. Further studies are warranted. (Echocardiography 2012;29:131-139) [ABSTRACT FROM AUTHOR]
- Subjects :
- ANALYSIS of covariance
ANALYSIS of variance
BLACK people
CARDIOVASCULAR diseases
CHI-squared test
STATISTICAL correlation
LEFT heart ventricle
INTERVIEWING
LUNGS
PULMONARY function tests
QUESTIONNAIRES
REGRESSION analysis
RESEARCH funding
RESPIRATORY measurements
SEX distribution
T-test (Statistics)
CONTINUING education units
VITAL capacity (Respiration)
DATA analysis software
DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 07422822
- Volume :
- 29
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Echocardiography
- Publication Type :
- Academic Journal
- Accession number :
- 70606645
- Full Text :
- https://doi.org/10.1111/j.1540-8175.2011.01550.x