Clinical Features of Hemoglobin C[subHarlem], A New Sickling Hemoglobin Variant.

Discusses the clinical features associated with the presence of hemoglobin C[subH]. Details of the case of a 45-year-old man who observed erythrocyte sickling associated with a paper electrophoretic pattern of hemoglobin C and A; Clinical manifestations of the hemoglobinopathy; Clinical implications of the structure and properties of the hemoglobin; Determination of the maximum urinary osmolality; Evaluation of renal concentrating ability.