Back to Search
Start Over
High resolution MRI of the breast at 3 T: which BI-RADS® descriptors are most strongly associated with the diagnosis of breast cancer?
- Source :
- European Radiology; Feb2012, Vol. 22 Issue 2, p322-330, 9p, 2 Charts, 3 Graphs
- Publication Year :
- 2012
-
Abstract
- Objective: To identify which breast lesion descriptors in the ACR BI-RADS® MRI lexicon are most strongly associated with the diagnosis of breast cancer when performing breast MR imaging at 3 T. Methods: 150 patients underwent breast MR imaging at 3 T. Lesion size, morphology and enhancement kinetics were assessed according to the BI-RADS® classification. Sensitivity, specificity and diagnostic accuracy were assessed. The effects of the BI-RADS® descriptors on sensitivity and specificity were evaluated. Data were analysed using logistic regression. Histopathological diagnoses were used as the standard of reference. Results: The sensitivity, specificity and diagnostic accuracy of breast MRI at 3 T was 99%, 81% and 93%, respectively. In univariate analysis, the final diagnosis of malignancy was positively associated with irregular shape ( p < 0.001), irregular margin ( p < 0.001), heterogeneous enhancement ( p < 0.001), Type 3 enhancement kinetics ( p = 0.02), increasing patient age ( p = 0.02) and larger lesion size ( p < 0.001). In multivariate analysis, significant associations with malignancy remained for mass shape ( p = 0.06), mass margin ( p < 0.001), internal enhancement pattern ( p = 0.03) and Type 3 enhancement kinetics ( p = 0.06). Conclusion: The ACR BI-RADS® breast lesion descriptors that are mostly strongly associated with breast cancer in breast MR imaging at 3 T are lesion shape, lesion margin, internal enhancement pattern and Type 3 enhancement kinetics. Key Points: • 3 Tesla breast MRI allows an accurate diagnosis of breast cancer • The BI-RADS® descriptors help provide a confident diagnosis • The shape, margin, enhancement pattern and kinetics are the most important features • An irregular shape and margin, heterogeneous enhancement and type-3 kinetics indicate malignancy [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09387994
- Volume :
- 22
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- European Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 70068919
- Full Text :
- https://doi.org/10.1007/s00330-011-2256-6