CHARACTERIZATION OF A NOVEL ENTAMOEBA HISTOLYTICA STRAIN FROM BURKINA FASO, AFRICA, POSSESSING A UNIQUE HEXOKINASE-2 GENE.

The article discusses a study which characterized Entamoeba histolytica strain (BF-841) originating from Burkina Faso. The hexokinase-2 (HXK-2) gene of BF-841 cl1 had amino acid variations at four positions compared to the sequence of an Entamoeba hystolica strain (HM-1: IMSS cl6). The study showed no difference in the substrate specificity of HXK (HXK-1 and HXK-2) between BF-841 cl1 and the references of Entamoeba hystolica strains including HM-1:iMSS cl6, SAW755 clB and KU27. BF-841 cl1 was confirmed to form liver abscesses in Syrian hamsters.