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High Functionalization of 5-Nitro-1H-imidazole Derivatives: The TDAE Approach.
- Source :
- Molecules; Aug2011, Vol. 16 Issue 8, p6883-6893, 11p, 2 Diagrams, 1 Chart
- Publication Year :
- 2011
-
Abstract
- We report herein the synthesis of substituted 2-[4-(1,2-dimethyl-5-nitro-1Himidazol-4-yl)phenyl]-1-arylethanols, ethyl 3-[4-(1,2-dimethyl-5-nitro-1H-imidazol-4-yl)-phenyl]-2-hydroxypropanoate and 2-[4-(1,2-dimethyl-5-nitro-1H-imidazol-4-yl)benzyl]-2-hydroxy-acenaphthylen-1(2H)-one from the reactions of 4-[4-(chloromethyl)phenyl]-1,2- dimethyl-5-nitro-1H-imidazole with various aromatic carbonyl and a-carbonyl ester derivatives using tetrakis(dimethylamino)ethylene (TDAE) methodology. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 16
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- 67705718
- Full Text :
- https://doi.org/10.3390/molecules16086883