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Which Method of GFR Estimation Has the Best Prognostic Value in Patients Treated with Primary PCI: Cockcroft-Gault Formula, MDRD, or CKD-EPI Equation?-A 6-Year Follow-Up.
- Source :
- Renal Failure; 2011, Vol. 33 Issue 10, p983-989, 7p, 3 Charts, 2 Graphs
- Publication Year :
- 2011
-
Abstract
- Background/aims: The aim of this study was to determine the correlation between renal function and 6-year mortality in patients with acute myocardial infarction (AMI), treated successfully with primary percutaneous coronary intervention (PCI), and to examine whether Cockcroft-Gault (C-G) formula or Modification of Diet in Renal Disease (MDRD) study equation or CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation is the best predictor of very late mortality. Methods: A prospective cohort study with 6-year follow-up of a homogenous group of 193 patients, with ST-segment elevation AMI treated with successful primary PCI. Glomerular filtration rate (GFR) estimated by C-G formula, MDRD, and CKD-EPI equation were analyzed. Results: The patients with chronic kidney disease (CKD) had a much lower cumulative survival rate than those without it ( p < 0.05). A larger area under the receiver-operating characteristic curve for death with respect to GFR for C-G formula was observed. In the multivariate analysis, only GFR ≥ 55 mL/min according to C-G formula was independently associated with lower mortality. Conclusion: CKD is associated with higher mortality after a successful primary PCI during a 6-year follow-up. C-G formula is better than MDRD and CKD-EPI equations at predicting mortality after AMI. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0886022X
- Volume :
- 33
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Renal Failure
- Publication Type :
- Academic Journal
- Accession number :
- 66715595
- Full Text :
- https://doi.org/10.3109/0886022X.2011.618922