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Neonatal hepatitis syndrome and alpha-1-antitrypsin deficiency: an epidemiological study in south-east England.
- Source :
- Postgraduate Medical Journal; Jun1974, Vol. 50 Issue 584, p376-380, 5p
- Publication Year :
- 1974
-
Abstract
- A prospective epidemiological study of the Neonatal Hepatitis Syndrome in S.E. England showed Alpha-1-Antitrypsin Deficiency (Pi ZZ) to be present in seven out of fifty-two patients. Data are considered from these seven patients, and from a further six cases from outside this area. The nature of acute illness, pathological changes on early liver biopsy, and short-term prognosis show considerable variability, but in general the hepatitis is more severe in patients with Alpha-1-A.T. deficiency than in those in whom no aetiological factor was found. [ABSTRACT FROM PUBLISHER]
- Subjects :
- ALPHA 1-antitrypsin deficiency
HEPATITIS
NEONATAL diseases
LONGITUDINAL method
Subjects
Details
- Language :
- English
- ISSN :
- 00325473
- Volume :
- 50
- Issue :
- 584
- Database :
- Complementary Index
- Journal :
- Postgraduate Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 66063669