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Metabolism of immunoglobulin A, lymphocyte function, and histocompatibility antigens in patients on anticonvulsants.
- Source :
- Journal of Neurology, Neurosurgery & Psychiatry; Apr1978, Vol. 41 Issue 4, p307-311, 5p, 3 Charts, 2 Graphs
- Publication Year :
- 1978
-
Abstract
- Low serum IgA levels were found in patients taking phenytoin, together with evidence of depressed T cell function. There was no correlation between the dose or the serum level. A correlation was found, however, with HL-A status, patients with a low IgA showing increased frequency of HL-A2. It is suggested that epileptic patients with HL-A2 status are likely to develop IgA deficiency when given phenytoin. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00223050
- Volume :
- 41
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Neurology, Neurosurgery & Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 66059117