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Testing a Level of Response to Alcohol-Based Model of Heavy Drinking and Alcohol Problems in 1,905 17-year-olds.
- Source :
- Alcoholism: Clinical & Experimental Research; Oct2011, Vol. 35 Issue 10, p1897-1904, 0p
- Publication Year :
- 2011
-
Abstract
- Background: The low level of response (LR) to alcohol is one of several genetically influenced characteristics that increase the risk for heavy drinking and alcohol problems. Efforts to understand how LR operates through additional life influences have been carried out primarily in modest-sized U.S.-based samples with limited statistical power, raising questions about generalizability and about the importance of components with smaller effects. This study evaluates a full LR-based model of risk in a large sample of adolescents from the United Kingdom. Methods: Cross-sectional structural equation models were used for the approximate first half of the age 17 subjects assessed by the Avon Longitudinal Study of Parents and Children, generating data on 1,905 adolescents (mean age 17.8 years, 44.2% boys). LR was measured with the Self-Rating of the Effects of Alcohol Questionnaire, outcomes were based on drinking quantities and problems, and standardized questionnaires were used to evaluate peer substance use, alcohol expectancies, and using alcohol to cope with stress. Results: In this young and large U.K. sample, a low LR related to more adverse alcohol outcomes both directly and through partial mediation by all 3 additional key variables (peer substance use, expectancies, and coping). The models were similar in boys and girls. Conclusions: These results confirm key elements of the hypothesized LR-based model in a large U.K. sample, supporting some generalizability beyond U.S. groups. They also indicate that with enough statistical power, multiple elements contribute to how LR relates to alcohol outcomes and reinforce the applicability of the model to both genders. [ABSTRACT FROM AUTHOR]
- Subjects :
- ALCOHOLISM
ALCOHOLISM risk factors
PSYCHOLOGICAL adaptation
ALCOHOLS (Chemical class)
ANALYSIS of covariance
ANALYSIS of variance
CONFIDENCE intervals
STATISTICAL correlation
ALCOHOL drinking
FACTOR analysis
GOODNESS-of-fit tests
MATHEMATICAL models
RELIABILITY (Personality trait)
RESEARCH funding
SEX distribution
PSYCHOLOGICAL stress
THEORY
AFFINITY groups
SECONDARY analysis
STRUCTURAL equation modeling
MAXIMUM likelihood statistics
CROSS-sectional method
DATA analysis software
ADOLESCENCE
GENETICS
Subjects
Details
- Language :
- English
- Volume :
- 35
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Alcoholism: Clinical & Experimental Research
- Publication Type :
- Academic Journal
- Accession number :
- 65833621
- Full Text :
- https://doi.org/10.1111/j.1530-0277.2011.01536.x