Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: A pathway to overcome cell barriers to drug and gene delivery.

Authors :: McIntosh, Deirdre P.
Xiang-Yang Tan
Oh, Phil
Schnitzer, Jan E.
Source :: Proceedings of the National Academy of Sciences of the United States of America; 2/19/2002, Vol. 99 Issue 4, p1996, 6p, 14 Diagrams, 4 Graphs
Publication Year :: 2002
Abstract: Examines the targeting endothelium and tissue-specific transcytosis in vivo for drug and gene delivery. Use of antibody and subfractionation to generate monoclonal antibody for lung aveolae; Formation of free vesicles for selective and quantal transendothelial transport; Discussion on the methods for antibody production.

Language :: English
ISSN :: 00278424
Volume :: 99
Issue :: 4
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 6538348
Full Text :: https://doi.org/10.1073/pnas.251662398

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