Back to Search
Start Over
Effects of α-lipoic acid supplementation on malondialdehyde contents and superoxide dismutase in rat skeletal muscles.
- Source :
- Food Science & Biotechnology; Aug2011, Vol. 20 Issue 4, p1133-1136, 4p
- Publication Year :
- 2011
-
Abstract
- This study investigated the effects of α-lipoic acid (ALA) supplementation on the malondialdehyde (MDA) contents and superoxide dismutase (SOD) protein expression in rat skeletal muscles under non-exercising condition. Fourteen Sprague-Dawley male rats at the age of 6 weeks were randomly divided into 2 groups CS, (normal diet group, n=7) and AS (0.5% ALA supplemented diet group, n=7), and keep non-exercising condition for 4 weeks. The muscle MDA concentration of the AS group was significantly lower than that of the CS group in the both soleus and extensor digitorum longus muscles. The expressions of Cu/Zn-SOD and Mn-SOD proteins in the soleus muscle were significantly higher in the AS group than that in the CS group. From these results, ALA supplementation under non-exercising condition had a role in increasing of antioxidant enzymes in skeletal muscle types of rats. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 12267708
- Volume :
- 20
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Food Science & Biotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 65181265
- Full Text :
- https://doi.org/10.1007/s10068-011-0154-y