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SINGLE-ALLELE CORRECTION OF THE Dmo1 LOCUS IN CONGENIC ANIMALS SUBSTANTIALLY ATTENUATES OBESITY, DYSLIPDAEMIA AND DIABETES PHENOTYPES OF THE OLETF RAT.
- Source :
- Clinical & Experimental Pharmacology & Physiology; Jan/Feb2001, Vol. 28 Issue 1/2, p28, 15p, 2 Diagrams, 5 Charts, 22 Graphs
- Publication Year :
- 2001
-
Abstract
- Examines the single-allele correction of a genetic defect of the Dmo1 locus. Effect of the Dmo1 locus on lipid metabolism; Involvement of Dmo1 in glucose homeostasis after loading; Establishment of congenic rats by the BC4 generation.
- Subjects :
- GENETIC disorders
LIPID metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 03051870
- Volume :
- 28
- Issue :
- 1/2
- Database :
- Complementary Index
- Journal :
- Clinical & Experimental Pharmacology & Physiology
- Publication Type :
- Academic Journal
- Accession number :
- 6395322
- Full Text :
- https://doi.org/10.1046/j.1440-1681.2001.03391.x