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Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH.

Authors :
Sung-Eun Kim
Bahta, Medhanit
Lountos, George T.
Ulrich, Robert G.
Burke Jr, Terrence R.
Waugh, David S.
Source :
Acta Crystallographica: Section D (Wiley-Blackwell); Jul2011, Vol. 67 Issue 7, p639-645, 7p
Publication Year :
2011

Abstract

The article presents information on a research which examines the effectiveness of isothiazolidinone heterocycles as inhibitors of the Yersinia pestis protein tyrosine phosphate. Also included are the materials and methods used in the research as well as a discussion on the results of the study.

Details

Language :
English
ISSN :
09074449
Volume :
67
Issue :
7
Database :
Complementary Index
Journal :
Acta Crystallographica: Section D (Wiley-Blackwell)
Publication Type :
Academic Journal
Accession number :
63309882
Full Text :
https://doi.org/10.1107/s0907444911018610