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Periodontal disease and bisphosphonates induce osteonecrosis of the jaws in the rat.

Authors :
Aghaloo, Tara L
Kang, Ben
Sung, Eric C
Shoff, Michael
Ronconi, Matthew
Gotcher, Jack E
Bezouglaia, Olga
Dry, Sarah M
Tetradis, Sotirios
Source :
Journal of Bone & Mineral Research; Aug2011, Vol. 26 Issue 8, p1871-1882, 12p
Publication Year :
2011

Abstract

The article presents a study on the role of dental disease in the development of bisphosphonate (BP)-related osteonecrosis of the jaws (BRONJ). It discusses the experiment conducted on a rat model to determine whether periodontal disease and BPs could induce BRONJ. It explores the significance of BP interventions for risk of BRONJ development and osteoporotic patients.

Details

Language :
English
ISSN :
08840431
Volume :
26
Issue :
8
Database :
Complementary Index
Journal :
Journal of Bone & Mineral Research
Publication Type :
Academic Journal
Accession number :
62978038
Full Text :
https://doi.org/10.1002/jbmr.379