Isodicentric duplication of Philadelphia chromosome as a mechanism of resistance to dasatinib in a patient with chronic myeloid leukemia after resistance to imatinib.

Authors :: Loglisci, Giuseppina
Breccia, Massimo
Nanni, Mauro
Mancini, Marco
De Cuia, Rosa
Cannella, Laura
Salaroli, Adriano
Federico, Vincenzo
Serrao, Alessandra
Giovanna loglisci, Maria
Santopietro, Michelina
Alimena, Giuliana
Source :: Leukemia & Lymphoma; Jul2011, Vol. 52 Issue 7, p1372-1375, 4p, 1 Color Photograph
Publication Year :: 2011
Abstract: A letter to the editor is presented which discuses a case study of a 69-year-old woman diagnosed with chronic myeloid leukemia (CML) who had been dasatinib-resistant resulting to Philadelphia (Ph) chromosome isodicentric duplication.

Subjects :: LETTERS to the editor
CHRONIC myeloid leukemia
DRUG resistance in cancer cells
GENETICS
PATIENTS

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