Effect of Epithermal Neutrons on Viability of Glioblastoma Tumor Cells in Vitro.

Authors :: Mostovich, L. A.
Gubanova, N. V.
Kutsenko, O. S.
Aleinik, V. I.
Kuznetsov, A. S.
Makarov, A. N.
Sorokin, I. N.
Taskaev, S. Yu.
Nepomnyashchikh, G. I.
Grigor'eva, E. V.
Source :: Bulletin of Experimental Biology & Medicine; Jun2011, Vol. 151 Issue 2, p264-267, 4p, 1 Black and White Photograph, 1 Chart, 2 Graphs
Publication Year :: 2011
Abstract: We studied in vitro effect of epithermal neutrons in various doses on viability of glioblastoma U87 tumor cells. Increasing the dose from 1.9 to 4.1 Sv promoted cell death. Cytofluorimetric analysis revealed no activation of apoptosis in the irradiated cells, which attested to necrotic death of the tumor cells exposed to epithermal neutron radiation. [ABSTRACT FROM AUTHOR]

Subjects :: GLIOBLASTOMA multiforme
CANCER cells
CELL proliferation
APOPTOSIS
BORON-neutron capture therapy
CYTOFLUOROMETRY

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