A low fructose diet in the treatment of pediatric obesity: A pilot study.

Background: Over the last three decades the prevalence of overweight and obesity has increased dramatically among children and adolescents worldwide. As the results of animal and human studies suggest that a diet rich in fructose may be a risk factor for the development of overweight, the aim of the pilot study was to evaluate if a dietary counseling aimed at a moderate reduction of dietary fructose intake (-50% in comparison to intake at baseline) has a positive effect on the body mass index (BMI) of overweight and obese children. Methods: Fifteen overweight or obese children aged 5-8 years were included into the 3 month dietary intervention study. At baseline and after 4 and 8 weeks children and their parents were trained to reduce fructose in the children's diet. Anthropometric parameters for calculating BMI and BMI standard deviation scores (BMI-SDS) as well as nutritional intake were assessed at baseline, after the 12-week intervention and after 12 week of follow up. Results: After the 12-week intervention children had significantly reduced their total energy, fructose, sucrose and glucose intake. BMI and BMI-SDS were significantly reduced by 0.68 kg/m² and 0.21, respectively, at the end of the intervention. At follow up, the BMI-SDS was significantly lower in comparison to baseline while the BMI was only decreased by trend (P = 0.08). Conclusions: The results of our pilot study indicate that counseling aimed towards a moderate reduction of dietary fructose and/or general sugar intake may have a positive effect on BMI in overweight and obese children. [ABSTRACT FROM AUTHOR]