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X-ray structure of acarbose bound to amylomaltase from Thermus aquaticus: Implications for the synthesis of large cyclic glucans.
- Source :
- European Journal of Biochemistry; Dec2000 Part 1, Vol. 267 Issue 23, p6903, 11p, 6 Color Photographs, 4 Diagrams, 2 Charts
- Publication Year :
- 2000
-
Abstract
- Examines the X-ray structure of acarbose from Thermus aquaticus. Determination on the inhibitory cyclitol ring of acarbose; Mechanisms of intramolecular cyclization; Analysis on the inhibitory action of acarbose on alpha-hydrolases.
- Subjects :
- ACARBOSE
RING formation (Chemistry)
HYDROLASES
Subjects
Details
- Language :
- English
- ISSN :
- 00142956
- Volume :
- 267
- Issue :
- 23
- Database :
- Complementary Index
- Journal :
- European Journal of Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 6124055
- Full Text :
- https://doi.org/10.1046/j.1432-1033.2000.01790.x