Analysis of expression of nuclear factor kappaB (NF-kappaB) in multiple myeloma: downregulation of NF-kappaB induces apoptosis.

Demonstrates that constitutively active nuclear factor-*kappaB (NF-κ B) is present both in myeloma cell lines as well as in primary multiple myeloma (MM) cells. Analysis of NF-κ B status in primary samples from patients with MM; Evaluation of constitutive activation of NF-κ B; Use of adenovirus vector with dominant negative I*kappa B α.