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Age-related changes of serum N-acetyl-aspartate in healthy controls.

Authors :
Ruggieri, Maddalena
Tortorella, Carla
Ceci, Edmondo
Paolicelli, Damiano
Solfrizzi, Vincenzo
Di Bitonto, Giovanna
Pica, Carmela
Mastrapasqua, Mariangela
Livrea, Paolo
Trojano, Maria
Source :
Age & Ageing; May2011, Vol. 40 Issue 3, p391-395, 5p, 1 Chart, 1 Graph
Publication Year :
2011

Abstract

The article discusses a study on the changes of N-acetyl-aspartate serum (NAA) levels in healthy controls (HCs) with respect to the HCs' age. It says that the study implemented the liquid chromatography-mass spectrometry (LC-MS) with stable isotope dilution and the multivariate analysis of variance to define the association of age and gender in serum levels. Results of the study reveal the connection of reduced NAA serum levels with ageing.

Details

Language :
English
ISSN :
00020729
Volume :
40
Issue :
3
Database :
Complementary Index
Journal :
Age & Ageing
Publication Type :
Academic Journal
Accession number :
60265034
Full Text :
https://doi.org/10.1093/ageing/afr021