Phase variation of a β-1,3 galactosyltransferase involved in generation of the ganglioside GM[sub1]-like lip-oligosaccharide of Campylobacter jejuni.

Authors :: Linton, Dennis
Gilbert, Michel
Hitchen, Paul G.
Dell, Anne
Morris, Howard R.
Wakarchuk, Warren W.
Gregson, Norman A.
Wren, Brendan W.
Source :: Molecular Microbiology; Aug2000, Vol. 37 Issue 3, p501, 14p, 3 Black and White Photographs, 4 Diagrams, 1 Chart, 7 Graphs
Publication Year :: 2000
Abstract: Examines the importance of ganglioside mimicry by Campylobacter jejuni lipooligosaccharide (LOS) in triggering the Miller-Fisher syndrome neuropathies. Identification of genes involved in the biosynthesis of ganglioside mimicking LOS; Increase of the electrophoretic mobility of LOS molecule; Presence of intragenic homopolymeric tract renders.

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