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Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/β-catenin signalling....
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; 12/18/2001, Vol. 98 Issue 26, p14973, 6p, 2 Diagrams, 5 Graphs
- Publication Year :
- 2001
-
Abstract
- Determines the activation of Wnt/beta-catenin pathway in human colon cancers. Effect of beta-catenin antisense oligodeoxynucleotides on the level of axin2 and human naked cuticle (hnkd) mRNA; Expression of axin2 and hnkd in colon cancer cell lines; Correlation of the increased expression of axin2 and hnkd with truncations in polyposis coli.
- Subjects :
- COLON cancer
NUCLEOTIDES
MESSENGER RNA
CELL lines
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 98
- Issue :
- 26
- Database :
- Complementary Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 5932606
- Full Text :
- https://doi.org/10.1073/pnas.261574498