A glycerol α- d-glucuronide and a megastigmane glycoside from the leaves of Guettarda speciosa L.

From the 1-BuOH-soluble fraction of a MeOH extract of the leaves of Guettarda speciosa L., two new compounds ( 1, 2) were isolated together with six known compounds. Spectroscopic analysis of 1 and 2 established their structures to be derivatives of a glycerol α-glucuronide and a megastigmane glycoside, respectively. HPLC analysis of the hydrolyzate of 1 confirmed the presence of d-glucuronic acid in the structure, and the modified Mosher's method established the absolute structure of 2. [ABSTRACT FROM AUTHOR]