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2009 Swine-Origin Influenza A (H1N1) Resembles Previous Influenza Isolates.
- Source :
- PLoS ONE; 2009, Vol. 4 Issue 7, p1-6, 6p, 1 Diagram, 2 Graphs
- Publication Year :
- 2009
-
Abstract
- Background: In April 2009, novel swine-origin influenza viruses (S-OIV) were identified in patients from Mexico and the United States. The viruses were genetically characterized as a novel influenza A (H1N1) strain originating in swine, and within a very short time the S-OIV strain spread across the globe via human-to-human contact. Methodology: We conducted a comprehensive computational search of all available sequences of the surface proteins of H1N1 swine influenza isolates and found that a similar strain to S-OIV appeared in Thailand in 2000. The earlier isolates caused infections in pigs but only one sequenced human case, A/Thailand/271/2005 (H1N1). Significance: Differences between the Thai cases and S-OIV may help shed light on the ability of the current outbreak strain to spread rapidly among humans. [ABSTRACT FROM AUTHOR]
- Subjects :
- SWINE influenza
H1N1 influenza
INFLUENZA viruses
NEURAMINIDASE
HEMAGGLUTININ
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 4
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- PLoS ONE
- Publication Type :
- Academic Journal
- Accession number :
- 58519040
- Full Text :
- https://doi.org/10.1371/journal.pone.0006402