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Carboxyamido-Triazole (CAI)- a Novel 'static' Signal Transduction Inhibitor Induces Apoptosis in Human Β-Cell Chronic Lymphocytic Leukemia Cells.

Authors :
Waselenko, Jamie K.
Shinn, Charlotte A.
Willis, Carl R.
Flinn, Ian W.
Grever, Michael R.
Byrd, John C.
Source :
Leukemia & Lymphoma; Sep2001, Vol. 42 Issue 5, p1049, 5p
Publication Year :
2001

Abstract

Investigates the induction of apoptosis in human B-cell chronic lymphocytic leukemia (CLL) cells by carboxyamido-triazole (CAI), a novel 'static' signal transduction inhibitor. Patient characteristics; Role of tumor reduction and disease stabilization in CLL; Detection of apoptosis in CLL cells.

Details

Language :
English
ISSN :
10428194
Volume :
42
Issue :
5
Database :
Complementary Index
Journal :
Leukemia & Lymphoma
Publication Type :
Academic Journal
Accession number :
5833535
Full Text :
https://doi.org/10.3109/10428190109097725