Upregulation of mRNA for the Melanocortin-1 Receptor but not for Melanogenic Proteins in Macrophage × Melanoma Fusion Hybrids Exhibiting Increased Melanogenic and Metastatic Potential.

Authors :: Chakraborty, Ashok K.
Funasaka, Yuko
Ichihashi, Masamitsu
Sodi, Stefano
Bhattacharya, Mahasweta
Pawelek, John
Source :: Pigment Cell Research; Dec99, Vol. 12 Issue 6, p355, 12p
Publication Year :: 1999
Abstract: Analyzes the expression of genes for tyrosinase, tyrosinase-related protein 1, tyrosinase-related protein 2 and melanocortin-1 receptor using reverse transcription polymerase chain reaction. Result of the incubation of melanocyte-stimulating hormone/isobutylmethylxanthine; Correlation of the abundance and gel mobility pattern with changes in activity in hybrids and parental melanoma cells.

Full Text Access

Tools