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High-performance liquid chromatography coupled to mass spectrometry for studying new pharmaceutical entities.

Authors :
Chernetsova, E. S.
Koryakova, A. G.
Source :
Journal of Analytical Chemistry; Dec2010, Vol. 65 Issue 14, p1436-1445, 10p, 1 Chart
Publication Year :
2010

Abstract

The review covers the aspects of the use of high-performance liquid chromatography coupled to mass spectrometry for studying new pharmaceutical entities. Attention is paid mainly to pharmacokinetic investigations. Different methods of sample preparation and approaches to minimize the duration of the analysis are discussed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10619348
Volume :
65
Issue :
14
Database :
Complementary Index
Journal :
Journal of Analytical Chemistry
Publication Type :
Academic Journal
Accession number :
57941817
Full Text :
https://doi.org/10.1134/S1061934810140029