Antimycotic effects of octenidine and pirtenidine.

Authors :: Ghannoum, M. A.
Elteen, K. Abu
Ellabib, M.
Whittaker, P. A.
Elteen, K A
Source :: Journal of Antimicrobial Chemotherapy (JAC); Feb1990, Vol. 25 Issue 2, p237-245, 9p
Publication Year :: 1990
Abstract: The effects of octenidine and pirtenidine on yeasts (in particular Candida albicans) have been studied. MIC and MCC values have been established as well as the inhibitory effects on growth, budding and germ tube formation. The drugs were shown to cause extensive leakage of cytoplasmic contents from the cells which was correlated with morphological and ultrastructural changes in the yeast. [ABSTRACT FROM AUTHOR]

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