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One-Pot Preparation of 2,5-Dichloro-4'-phenyloxybenzophenone.

Authors :
Davis, MatthewC.
Groshens, ThomasJ.
Source :
Synthetic Communications; 2011, Vol. 41 Issue 2, p255-261, 7p
Publication Year :
2011

Abstract

Friedel-Crafts-type acylation of phenyl ether with 2,5-dichlorobenzoic acid could be accomplished in a single step using trifluoroacetic anhydride and phosphoric acid. The method gave a greater yield (78%) than the conventional two-step process (71%) of acid chloride generation followed by aluminum trichloride-mediated acylation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397911
Volume :
41
Issue :
2
Database :
Complementary Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
56043394
Full Text :
https://doi.org/10.1080/00397910903534056