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Phosphorylative inactivation of rifampicin by Nocardia otitidiscaviarum.
- Source :
- Journal of Antimicrobial Chemotherapy (JAC); Jun1994, Vol. 33 Issue 6, p1127-1135, 9p
- Publication Year :
- 1994
-
Abstract
- Rifampicin was inactivated by Nocardia otitidiscaviarum to yield two products designated RIP-3 and RIP-4. The full structures of RIP-3 and RIP-4 were determined to be 21-(O-phosphoryl) rifampicin and 3-formyl-21-(O-phosphoryl) rifamycin SV, respectively, but neither product had any antimicrobial activity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03057453
- Volume :
- 33
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Journal of Antimicrobial Chemotherapy (JAC)
- Publication Type :
- Academic Journal
- Accession number :
- 55971054