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Cerebrospinal fluid insulin during non-neurological surgery.
- Source :
- Journal of Neural Transmission; Oct2010, Vol. 117 Issue 10, p1167-1170, 4p, 1 Chart, 1 Graph
- Publication Year :
- 2010
-
Abstract
- Insulin plays an important metabolic and transmitter role in the central nervous system, but few studies have investigated the relationship between central and peripheral insulin concentrations. 35 patients undergoing knee surgery had cerebrospinal fluid (CSF) samples drawn before, 3 h after, and in the morning following surgery. Serum insulin concentrations increased after surgery and CSF insulin concentrations changed in the same direction with far smaller amplitude. These results indicate that the blood-brain barrier protects the brain from stress-induced peripheral hormonal fluctuations. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03009564
- Volume :
- 117
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Journal of Neural Transmission
- Publication Type :
- Academic Journal
- Accession number :
- 55471071
- Full Text :
- https://doi.org/10.1007/s00702-010-0456-x