Synthesis of ethyl (±)-(13,15-dideoxy)-16-methyl-9-oxoprosta-13( E,Z),15( E)-dienoate.

Authors :: Vostrikov, N. S.
Loza, V. V.
Ivanova, N. A.
Miftakhov, M. S.
Source :: Russian Journal of Organic Chemistry; Sep2010, Vol. 46 Issue 9, p1301-1304, 4p, 5 Diagrams
Publication Year :: 2010
Abstract: The condensation of ethyl 7-(2-oxo-5-formulcyclopentyl)heptanoate by Wittig reaction with the ylide prepared from [(2 E)-3-methylhept-2-en-1-yl]triphenylphosphonium bromide afforded ethyl (±)-(13,15-dideoxy)-16-methyl-9-oxoprosta-13( E,Z),15( E)-dienoate as a mixture of two isomers, 2:1. [ABSTRACT FROM AUTHOR]

Subjects :: GASTROINTESTINAL disease treatment
ETHYLENE synthesis
WITTIG reaction
YLIDES
PROSTAGLANDINS
MISOPROSTOL

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