Effect of Acamprosate on Magnetic Resonance Spectroscopy Measures of Central Glutamate in Detoxified Alcohol-Dependent Individuals.

The article discusses a study on the impact of acamprosate on the central glutamate levels in alcohol-addicted people as estimated through magnetic resonance spectroscopy (MRS). The study conducted a 4-week random medical experiment involving 33 alcohol-dependent patients at the U.S. National Institutes of Health Clinical Center. The study concluded that the MRS measures of central glutamate decline as time passes when acamprostate therapy is performed during the process of patients avoiding alcohol intake.