Study of acylation reactions in 3-aminocarbostyril derivatives.

ylation of 3-amino-1(2H)-isoquinolinone may proceed at three points - at the oxygen atom of the carbonyl group, at the nitrogen atom of the 3-amino group, and at the carbon atom in position 4 of the isoquinolinone fragment. Factors influencing the results of the reactions have been determined, and conditions have been found for the synthesis of three types of products - 4-(acyl)-3-(R-amino)-1(2H)-isoquinolinones, N-(1-oxo-1,2-dihydro-3-isoquinolinyl)-R-amides, and esters of 3-(R-amino)-1-iso-quinolinol. [ABSTRACT FROM AUTHOR]