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SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis.
- Source :
- European Heart Journal; Sep2010, Vol. 31 Issue 18, p2301-2309, 9p, 5 Graphs
- Publication Year :
- 2010
-
Abstract
- Aims: Endothelial activation, macrophage infiltration, and foam cell formation are pivotal steps in atherogenesis. Our aim in this study was to analyse the role of SIRT1, a class III deacetylase with important metabolic functions, in plaque macrophages and atherogenesis. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 0195668X
- Volume :
- 31
- Issue :
- 18
- Database :
- Complementary Index
- Journal :
- European Heart Journal
- Publication Type :
- Academic Journal
- Accession number :
- 53718964
- Full Text :
- https://doi.org/10.1093/eurheartj/ehq107