Back to Search
Start Over
Conservation of progesterone hormone function in invertebrate reproduction.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; 6/29/2010, Vol. 107 Issue 26, p11859-11864, 6p
- Publication Year :
- 2010
-
Abstract
- Steroids play fundamental roles regulating mammalian reproduction and development Although sex steroids and their receptors are well characterized in vertebrates and several arthropod invertebrates, little is known about the hormones and receptors regulating reproduction in other invertebrate species. Evolutionary insights into ancient endocrine pathways can be gained by elucidating the hormones and receptors functioning in invertebrate reproduction. Using a combination of genomic analyses, receptor imaging, ligand identification, target elucidation, and exploration of function through receptor knockdown, we now show that comparable progesterone chemoreception exists in the invertebrate monogonont rotifer Brachionus manjavacas suggesting an ancient origin of the signal transduction systems commonly associated with the development and integration of sexual behavior in mammals. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 107
- Issue :
- 26
- Database :
- Complementary Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 52237654
- Full Text :
- https://doi.org/10.1073/pnas.1006074107