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Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetyicholinesterase inhibitied by pa raoxon.
- Source :
- Journal of Applied Toxicology; Jan/Feb2006, Vol. 26 Issue 1, p64-71, 8p, 6 Charts, 6 Graphs
- Publication Year :
- 2006
-
Abstract
- The article presents a study which compared the importance of oximes and pralidoxime (PRX) for in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon (POX), a non-neuropathic organophosphate. The study found that the new cholinesterase reactivators are superior to PRX, methoxime and B1-6, K-27 oximes. It discovered the importance of in vivo testing in determining the efficacy of new oximes in treating organophosphorus compounds-induced poisoning.
Details
- Language :
- English
- ISSN :
- 0260437X
- Volume :
- 26
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Applied Toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 52047284
- Full Text :
- https://doi.org/10.1002/jat.1108