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COPD Is Associated With a Macrophage Scavenger Receptor-1 Gene Sequence Variation.

Authors :
Ohar, Jill A.
Hamilton Jr., Raymond F.
Siqun Zheng
Sadeghnejad, Alireza
Sterling, David A.
Jianfeng Xu
Meyers, Deborah A.
Bleecker, Eugene R.
Holian, Andrij
Source :
CHEST; May2010, Vol. 137 Issue 5, p1098-1107, 10p, 3 Charts, 5 Graphs
Publication Year :
2010

Abstract

The article presents research of Jill A. Ohar and team to assess the role of macrophage scavenger receptor-1 (MSR1) gene sequence variation in chronic pulmonary disease (COPD) of patients in the U.S. Researchers assessed smokers more than 40 years old and found that macrophages play an vital role in regulating pulmonary inflammation and parenchymal destruction with COPD. Moreover, they found that MSR1 is associated with COPD susceptibility.

Details

Language :
English
ISSN :
00123692
Volume :
137
Issue :
5
Database :
Complementary Index
Journal :
CHEST
Publication Type :
Academic Journal
Accession number :
50612432
Full Text :
https://doi.org/10.1378/chest.09-1655