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Temperature-Controlled Radiofrequency Catheter Ablation with a 10-mm Tip Electrode Creates Larger Lesions without Charring in the Porcine Heart.

Authors :
Anfinsen, Ole-Gunnar
Aass, Halfdan
Kongsgaard, Erik
Foerster, Arnold
Scott, Helge
Amlie, Jan
Source :
Journal of Interventional Cardiac Electrophysiology; Dec1999, Vol. 3 Issue 4, p343-351, 9p
Publication Year :
1999

Abstract

Background: Radiofrequency catheter ablation of atrial flutter, atrial fibrillation or ventricular tachycardia may be favoured by large lesions. We compared lesions created in unipolar mode using 10-mm/8 F electrodes with those of 4-mm/7 F catheters. Methods: Ablations were first performed in porcine hearts in vitro (70°C, 60 s, tangential catheter tip-tissue orientation). Anaesthetized pigs were thereafter ablated with 10- or 4-mm catheters in the right atrial free wall (RAFW), inferior vena cava-tricuspid valve (IVC-TV) isthmus and left ventricle (LV). Results: In vitro, lesion length doubled and lesion volume tripled using the 10-mm catheter. Average power supply was 69 (SD12) (10-mm tip) versus 26 (SD7) W (4-mm tip). In vivo, lesion length increased by 50% and lesion volume fivefold. Charring at the lesion surface or sudden impedance rises were not observed in vivo. Histologically, coagulation necrosis and minor haemorrhages were found. One RAFW lesion (10-mm) showed a dissection approaching the epicardium. Fibrinous platelet clots or overt thromboses covered the endocardial surface in half of all lesions. Three 10-mm electrode isthmus lesions extended to the right descending posterior artery and one LV lesion to the left anterior descending artery, but there was no damage to the arterial walls. Following six ablations with the 10-mm electrode and two with the 4-mm tip, injury to the adjacent lung tissue of 0.5 to 6.0 mm depth was found (p = 0.22). Conclusion: RF ablation using 10-mm/8 F electrodes created significantly larger lesions. 10-mm electrodes appeared safe in the porcine IVC-TV isthmus and LV, but not in the RAFW. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1383875X
Volume :
3
Issue :
4
Database :
Complementary Index
Journal :
Journal of Interventional Cardiac Electrophysiology
Publication Type :
Academic Journal
Accession number :
50042983
Full Text :
https://doi.org/10.1023/A:1009840004782