Investigation of mass-transfer in occluded rat artery In Vivo.

The release of radiolabeled immunoglobulins from distal end of blocked rat carotid artery was studied in vivo. The elimination half-time was 8–9 min for a 4–5-cm long segment of blocked artery and 16–24 min for a 7–8-cm long segment. Surprisingly high rate of convection in completely blocked arteries under conditions of pulsatile pressure has been demonstrated. [ABSTRACT FROM AUTHOR]