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Smoking and smoking cessation during early pregnancy and its effect on adverse pregnancy outcomes and fetal growth.
- Source :
- European Journal of Pediatrics; Jun2010, Vol. 169 Issue 6, p741-748, 8p, 5 Charts
- Publication Year :
- 2010
-
Abstract
- Maternal smoking during pregnancy is a significant threat to the fetus. We examined the association between active maternal smoking and smoking cessation during early pregnancy with newborn somatometrics and adverse pregnancy outcomes including preterm delivery, low birth weight, and fetal growth restriction. One thousand four hundred mother-child pairs with extensive questionnaire data were followed up until delivery, within the context of a population-based mother-child cohort study (Rhea study), in Crete, Greece, 2007-2008. Comparing smokers to nonsmokers, the adjusted odds ratio (OR) was 2.8 [95% confidence interval (CI), 1.7, 4.6] for low birth weight and 2.6 (95%CI: 1.6, 4.2) for fetal growth restriction. This corresponded to a 119-g reduction in birth weight, a 0.53-cm reduction in length, and a 0.35-cm reduction in head circumference. Smoking cessation early during pregnancy modified significantly these pregnancy outcomes indicating the necessity for primary smoking prevention. [ABSTRACT FROM AUTHOR]
- Subjects :
- WOMEN'S tobacco use
PREGNANT women
FETAL development
PREGNANCY complications
PREMATURE labor
LOW birth weight
SMOKING prevention
BIRTH size
COMPARATIVE studies
FETAL growth retardation
IMMIGRANTS
PREMATURE infants
LONGITUDINAL method
RESEARCH methodology
EVALUATION of medical care
MEDICAL cooperation
PREGNANCY
QUESTIONNAIRES
REGRESSION analysis
RESEARCH
SMOKING
SMOKING cessation
LOGISTIC regression analysis
EVALUATION research
PREVENTION
Subjects
Details
- Language :
- English
- ISSN :
- 03406199
- Volume :
- 169
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- European Journal of Pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 49781141
- Full Text :
- https://doi.org/10.1007/s00431-009-1107-9