Comparison of the adsorption characteristics of expanded bed adsorbent with conventional chromatographic adsorbent.

The static and kinetic adsorption characteristics of Streamline DEAE and DEAE-Sepharose FF were studied under various operating conditions. The adsorption isotherms for the two types of adsorbents were obtained and found to fit well to a Langmuir-type expression. The adsorption kinetics of Streamline DEAE at different concentrations, temperatures, and viscosities were studied and a mathematical model including particle size distribution was developed to describe the adsorption performance of Streamline DEAE. Comparing the uptake curves of Streamline DEAE with DEAE-Sepharose FF, it could be concluded that Streamline DEAE achieves equilibrium faster to get equilibrium than DEAE-Sepharose FF, indicating that Streamline DEAE could be used in higher flow rate systems. [ABSTRACT FROM AUTHOR]